Adv Exp Med Biol. 1989;266:3-15. Lipofuscin and ceroid formation: the cellular recycling system. Harman D. Lipofuscin, age pigment, is a dark pigment with a strong autofluorescence seen with increasing frequency with advancing age in the cytoplasm of postmitotic cells. By bright-field light microscopy lipofuscin appears as irregular yellow to brown granules ranging in size from [...]