Browsing articles in "liver"
One of the essential protective functions that decline with aging is the liver’s ability to detoxify chemicals, by combining them by glucuronic acid, making them water soluble so that they can be excreted in the urine. The liver (and also the instestines and stomach) efficiently process DHA by glucuronidation. -Ray Peat, PhD Drug Metab Dispos. [...]
Also see: Thyroid peroxidase activity is inhibited by amino acids Gelatin, Glycine, and Metabolism Gelatin > Whey The selection of proteins should minimize the amino acids tryptophan (which is the precursor of serotonin) and cysteine (which, like tryptophan, suppresses thyroid function, by including gelatin and fruits. Gelatin is 22% glycine, which protects the lungs and [...]
Also see: Estrogen, Endotoxin, and Alcohol-Induced Liver Injury Alcohol Consumption – Estrogen and Progesterone In Women How does estrogen enhance endotoxin toxicity? Let me count the ways. J Korean Med Sci. 1999 Jun;14(3):277-85. The metabolic effects of estriol in female rat liver. Yang JM, Kim SS, Kim JI, Ahn BM, Choi SW, Kim JK, Lee [...]
Also See Alcohol Consumption – Estrogen and Progesterone In Women How does estrogen enhance endotoxin toxicity? Let me count the ways. PUFA and Liver Toxicity; Protection by Saturated Fats Endotoxin: Poisoning from the Inside Out Hepatology. 2000 Jan;31(1):117-23. Estrogen is involved in early alcohol-induced liver injury in a rat enteral feeding model. Yin M, Ikejima [...]
Alcohol and Alcoholism (2000) 35 (5): 417-423. THE EFFECTS OF MODERATE ALCOHOL CONSUMPTION ON FEMALE HORMONE LEVELS AND REPRODUCTIVE FUNCTION Studies that have investigated the effect of moderate alcohol consumption on the level of oestrogens and progesterone in both pre- and post-menopausal women are reviewed. It is concluded that several lines of evidence point to [...]
Endocrinology. 2003 Jun;144(6):2404-8. In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters. Hamel FG, Upward JL, Bennett RG. Insulin-degrading enzyme is responsible for initiating insulin degradation in cells, but little is known about the factors controlling its activity. Because obesity and high levels of free fatty acids decrease insulin [...]
Diabetes Care. 2007 Jun;30(6):1406-11. Epub 2007 Mar 23. Orange juice or fructose intake does not induce oxidative and inflammatory response. Ghanim H, Mohanty P, Pathak R, Chaudhuri A, Sia CL, Dandona P. OBJECTIVE: We have previously shown that 300 kcal from glucose intake induces a significant increase in reactive oxygen species (ROS) generation and nuclear [...]
For example, the flavonoids, naringenin, quercetin and kaempherol (kaempherol is an antioxidant, a phytoestrogen, and a mutagen) modify the metabolism of estradiol, causing increased bioavailability of both estrone and estradiol. (W. Schubert, et al., “Inhibition of 17-beta-estradiol metabolism by grapefruit juice in ovariectomized women,” Maturitas (Ireland) 30(2-3), 155-163, 1994.) -Ray Peat, PhD Maturitas. 1994 Dec;20(2-3):155-63. [...]
For example, the flavonoids, naringenin, quercetin and kaempherol (kaempherol is an antioxidant, a phytoestrogen, and a mutagen) modify the metabolism of estradiol, causing increased bioavailability of both estrone and estradiol. (W. Schubert, et al., “Inhibition of 17-beta-estradiol metabolism by grapefruit juice in ovariectomized women,” Maturitas (Ireland) 30(2-3), 155-163, 1994.) -Ray Peat, PhD Maturitas. 1994 Dec;20(2-3):155-63. [...]
Is 98.6 Really Normal? A great article provided by Women’s Health Connections that includes discussion of the work of Ray Peat, PhD and Broda Barnes, MD, PhD.
