Lancet. 2000 Sep 9;356(9233):930-3. The endotoxin-lipoprotein hypothesis. Rauchhaus M, Coats AJ, Anker SD. The advent of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) has revolutionised the treatment of hypercholesterolaemia. Statin treatment, by lowering the atherogenic lipoprotein profile, reduces morbidity and mortality in patients with cardiovascular disease. Treatment with simvastatin causes a reduction of events of new-onset heart [...]
by Barry Groves http://www.second-opinions.co.uk/immunity3.html There is a substantial amount of evidence that relatively low cholesterol levels in apparently healthy individuals is associated with increased subsequent mortality from cancer. It is also associated with other, non-heart related deaths. A group at the Center for Clinical Pharmacology, University of Pittsburgh, Pennsylvania, tested whether the effectiveness of their [...]