Also see: Uric Acid as an Antioxidant Clin Exp Rheumatol. 2001 Nov-Dec;19(6):661-5. Hyperuricemia and gout in thyroid endocrine disorders. Giordano N, Santacroce C, Mattii G, Geraci S, Amendola A, Gennari C. OBJECTIVE: A significant correlation between thyroid function and purine nucleotide metabolism has been established in hypothyroidism. On the contrary, the relationship between hyperthyroidism and [...]