One of the essential protective functions that decline with aging is the liver’s ability to detoxify chemicals, by combining them by glucuronic acid, making them water soluble so that they can be excreted in the urine. The liver (and also the instestines and stomach) efficiently process DHA by glucuronidation. -Ray Peat, PhD Drug Metab Dispos. [...]
One of the essential protective functions that decline with aging is the liver’s ability to detoxify chemicals, by combining them by glucuronic acid, making them water soluble so that they can be excreted in the urine. The liver (and also the instestines and stomach) efficiently process DHA by glucuronidation. -Ray Peat, PhD Drug Metab Dispos. [...]
For example, the flavonoids, naringenin, quercetin and kaempherol (kaempherol is an antioxidant, a phytoestrogen, and a mutagen) modify the metabolism of estradiol, causing increased bioavailability of both estrone and estradiol. (W. Schubert, et al., “Inhibition of 17-beta-estradiol metabolism by grapefruit juice in ovariectomized women,” Maturitas (Ireland) 30(2-3), 155-163, 1994.) -Ray Peat, PhD Maturitas. 1994 Dec;20(2-3):155-63. [...]
For example, the flavonoids, naringenin, quercetin and kaempherol (kaempherol is an antioxidant, a phytoestrogen, and a mutagen) modify the metabolism of estradiol, causing increased bioavailability of both estrone and estradiol. (W. Schubert, et al., “Inhibition of 17-beta-estradiol metabolism by grapefruit juice in ovariectomized women,” Maturitas (Ireland) 30(2-3), 155-163, 1994.) -Ray Peat, PhD Maturitas. 1994 Dec;20(2-3):155-63. [...]
