Hypothyroidism is a very common cause of increased serotonin (e.g. Henley, et al., 1998), and it the thyroid hormone is supplemented until symptoms are resolved, it’s likely that the serotonin will have been normalized. -Ray Peat, PhD Hypothyroidism increases the formation of serotonin, as does cortisol (Henley, et al., 1997, 1998; Neckers and Sze, 1976). [...]
FEBS Lett. 1998 Sep 11;435(1):25-8. Glucocorticoids decrease cytochrome c oxidase activity of isolated rat kidney mitochondria. Simon N, Jolliet P, Morin C, Zini R, Urien S, Tillement JP. The importance of mitochondria is rising as a target in pathologic processes such as ischemia. We have investigated the effects of hydrocortisone, prednisolone, dexamethasone and triamcinolone on [...]