Browsing articles in "General"
Intern Med. 1998 May;37(5):472-5. A hypopituitary patient who attained tall stature without growth hormone. Kageyama K, Watanobe H, Nasushita R, Nishie M, Horiba N, Suda T. We describe an unusual patient with hypopituitarism who attained tall stature even without growth hormone (GH). A 37-year-old man was devoid of secondary sexual characteristics, but manifested tall stature [...]
Intern Med. 1998 May;37(5):472-5. A hypopituitary patient who attained tall stature without growth hormone. Kageyama K, Watanobe H, Nasushita R, Nishie M, Horiba N, Suda T. We describe an unusual patient with hypopituitarism who attained tall stature even without growth hormone (GH). A 37-year-old man was devoid of secondary sexual characteristics, but manifested tall stature [...]
A 1994 publication (B. Zumoff, “Hormonal profiles in women with breast cancer,” Obstet. Gynecol. Clin. North. Am. (U.S.) 21(4), 751-772) reported that there are four hormonal features in women with breast cancer: diminished androgen production, luteal inadequacy, increased 16-hydroxylation of estradiol, and increased prolactin. The 16-hydroxylation converts estradiol into estriol. -Ray Peat, PhD Obstet Gynecol [...]
The thumbnail below is a revisable chart that portrays factors that promote efficient or inefficient energy metabolism. The goal of the health conscious should be to maximize the effects of the promoters of efficient metabolism while minimizing the effects of the factors that lead to inefficient metabolism. Some of the factors that promote inefficient metabolism [...]
J Strength Cond Res. 2010 Mar;24(3):639-43. Influence of supervision ratio on muscle adaptations to resistance training in nontrained subjects. Gentil P, Bottaro M. The purpose of the present study was to compare the changes in muscle strength in nontrained young males performing resistance training under different supervision ratios. One hundred twenty-four young men were randomly [...]
Also see: PUFA – Accumulation & Aging Free Fatty Acids Suppress Cellular Respiration “Curing” a High Metabolic Rate with Unsaturated Fats Fat Deficient Animals – Activity of Cytochrome Oxidase Randle Cycle Protective “Essential Fatty Acid Deficiency” Errors in Nutrition: Essential Fatty Acids With aging, cells have less ability to produce energy, and are often more [...]
“An excess of tryptophan in the diet, especially with deficiencies of other nutrients, can combine with inflammation to increase serotonin. Polyunsaturated fatty acids promote the absorption of tryptophan by the brain, and its conversion to serotonin. A “deficiency” of polyunsaturated fat decreases the expression of the enzyme that synthesizes serotonin (McNamara, et al., 2009). -Ray [...]
Hypothyroidism is a very common cause of increased serotonin (e.g. Henley, et al., 1998), and it the thyroid hormone is supplemented until symptoms are resolved, it’s likely that the serotonin will have been normalized. -Ray Peat, PhD Hypothyroidism increases the formation of serotonin, as does cortisol (Henley, et al., 1997, 1998; Neckers and Sze, 1976). [...]
Since estrogen promotes serotonin, progesterone is likely to be a protective factor (Donner & Handa, 2009; Hiroi, et al., 2006; Berman, et al., 2006; Bethea, et al., 2000). -Ray Peat, PhD Neuroscience. 2009 Oct 6;163(2):705-18. Epub 2009 Jun 23. Estrogen receptor beta regulates the expression of tryptophan-hydroxylase 2 mRNA within serotonergic neurons of the rat [...]
The Dire Effects of Estrogen Pollution By Ray Peat, PhD. Source Pollution of the environment and food supply by estrogenic chemicals is getting increased attention. Early in the study of estrogens, it was noticed that soot, containing polycyclic aromatic hydrocarbons, was both estrogenic and carcinogenic. Since then, it has been found that phenolics and chlorinated [...]
