Also see: The Randle Cycle Dietary salt restriction, which increases aldosterone levels, is also associated with an increase in insulin resistance. -Garg and Adler, 2012 Curr Opin Endocrinol Diabetes Obes. 2012 Jun;19(3):168-75. Role of mineralocorticoid receptor in insulin resistance. Garg R, Adler GK. PURPOSE OF REVIEW: Recent data suggest that mineralocorticoid receptor activation can affect [...]
ci. Aging Knowl. Environ., 25 September 2002 Vol. 2002, Issue 38, p. cp21 The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis Robert M. Sapolsky, Lewis C. Krey, and Bruce S. McEwen Abstract: Over the past 5 yr, we have examined some of the sharpest edges of the pathology of aging. We have studied [...]
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Also see: Fish Oil Toxicity PUFA, Fish Oil, and Alzheimers Women are known to have a greater susceptibility than men to lipolysis, with higher levels of free fatty acids in the serum and liver, because of the effects of estrogen and related hormones. Women on average have more DHA circulating in the serum than men [...]
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J Nutr. 2011 Sep;141(9):1635-42. Epub 2011 Jul 20. Ingestion of (n-3) fatty acids augments basal and platelet activating factor-induced permeability to dextran in the rat mesenteric vascular bed. Dombrowsky H, Lautenschläger I, Zehethofer N, Lindner B, Schultz H, Uhlig S, Frerichs I, Weiler N. Loss of intestinal barrier function and subsequent edema formation remains a [...]
Thymocytes are much more easily killed by stress than nerve cells, and they are easy to study. The PUFA kill them by increasing their intracellular calcium. The toxicity of DHA is greater than that of EPA, whose toxicity is greater than the alpha-linoleic acid, and linoleic acid was the most potent (Prasad, et al., 2010)…The [...]
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