Also see: High Cholesterol and Metabolism The Cholesterol and Thyroid Connection Thyroid Status and Oxidized LDL The Truth about Low Cholesterol Hypothyroidism and A Shift in Death Patterns Light is Right Using Sunlight to Sustain Life PUFA Decrease Cellular Energy Production PUFA Breakdown Products Depress Mitochondrial Respiration “Curing” a High Metabolic Rate with Unsaturated Fats [...]
Energy depletion itself is an excitatory state, that calls for increased fuel and oxygen. But when cells are exposed to PUFA, their ability to use glucose is blocked, increasing their exposure to the fats. Saturated fats activate the pyruvate dehydrogenase enzyme that is essential for the efficient use of glucose, while PUFA block it. -Ray Peat, [...]
Also see: ATP Regulates Cell Water Lactate Paradox: High Altitude and Exercise Trauma & Resuscitation: Toxicity of Lactated Ringer’s Solution Sodium Deficiency and Stress I have written previously about several dramatically effective treatments for shock that were developed in the last fifty years–for example intravenous ATP, concentrated solutions of sodium chloride or glucose, and the [...]
The thumbnail below is a revisable chart that portrays factors that promote efficient or inefficient energy metabolism. The goal of the health conscious should be to maximize the effects of the promoters of efficient metabolism while minimizing the effects of the factors that lead to inefficient metabolism. Some of the factors that promote inefficient metabolism [...]
Also see: PUFA, Fish Oil, and Alzheimers Biochemistry. 1998 Jan 13;37(2):552-7. Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal. Humphries KM, Yoo Y, Szweda LI. During the progression of certain degenerative conditions, including myocardial ischemia-reperfusion injury, mitochondria are a source of increased free-radical generation and exhibit declines in respiratory function(s). It has therefore been suggested that [...]
Male, 30 years old, Southern California What was the primary benefit of doing the Program for you? The knowledge of how the human body really works, and what it takes to truly nourish your body so it can heal. Did you experience changes in energy, appetite, emotional balance and mental sharpness? Yes, I experienced an [...]
by Ray Peat, PhD The biological idea of stress refers to the difficulty of adapting, and this involves energy, structure, and insight/orientation. Given enough energy, we can often adjust our structure to achieve full adaptation, and with insight, we can minimize the amount of energy and structural change needed, for example just by a change [...]
