Also see:
Low Blood Sugar Basics
Ray Peat, PhD on Low Blood Sugar & Stress Reaction
PUFA Promote Stress Response; Saturated Fats Suppress Stress Response
Protect the Mitochondria
Saturated and Monousaturated Fatty Acids Selectively Retained by Fat Cells
PUFA Decrease Cellular Energy Production
The Randle Cycle
Low Carb Diet – Death to Metabolism
Free Fatty Acid Suppress Cellular Respiration
Sugar (Sucrose) Restrains the Stress Response
Protection from Endotoxin
Possible Indicators of High Cortisol and Adrenaline
Thyroid peroxidase activity is inhibited by amino acids
Toxicity of Stored PUFA
Belly Fat, Cortisol, and Stress
Sugar (Sucrose) Restrains the Stress Response
PUFA, Development, and Allergy Incidence
Quotes by Ray Peat, PhD:
“Hypoglycemia (which can result from any respiratory defect) can produce malfunction of any tissue, but brain dysfunction and immune dysfunction are very common effects. Adamkiewicz has shown that allergic reactions to a given substance will decrease from 100 percent to zero, when the blood glucose increases from, for example, 50 mg. to 150 mg. or more.”
“Thyroid, progesterone and pregnenolone help to normalize the blood sugar by improving respiration, and should be the basic treatment for allergies.”
”…Blood sugar is usually the thing to pay most attention to, everything becomes an allergen if the glucose is chronically low. Thyroid is the main thing that stabilizes the blood sugar. Aspirin usually helps with allergies…”
“While Warburg was investigating the roles of glycolysis and respiration in cancer, a physician with a background in chemistry, W.F. Koch, in Detroit, was showing that the ability to use oxygen made the difference between health and sickness, and that the cancer metabolism could be corrected by restoring the efficient use of oxygen. He argued that a respiratory defect was responsible for immunodeficiency, allergy, and defective function of muscles, nerves, and secretory cells, as well as cancer.”
AJP – Legacy Content January 1960 vol. 198 no. 1 51-53
Glucose and the dextran ‘anaphylactoid’ inflammation
V. W. Adamkiewicz and Lidia M. Adamkiewicz
Male Sprague-Dawley rats, 120–150 gm in body weight, injected simultaneously with the glucan dextran (1 ml 6% w/v, i.p.) and with an overdose of glucose (3 x 5 ml, 25% w/v, s.c.) which cannot be markedly reduced by excretion in about 24 hours, do not undergo dextran ‘anaphylactoid’ inflammation. If the amount of glucose is smaller (2 x 5 ml, 25% w/v, s.c.) and can be reduced by excretion within about 10 hours, the inflammation occurs, but is greatly delayed in time and diminished in intensity. The specific inhibitory action glucose exerts on the biological activity of the glucan dextran is discussed.
The Journal of Immunology January 1, 1964 vol. 92 no. 1 3-7
Glycemic States and the Horse-Serum and Egg-White Anaphylactic Shock in Rats1
V. W. Adamkiewicz, P. J. Sacra and J. Ventura
The hypoglycemic state produced in rats by 48 hr fasting or by administration of 4 units of insulin aggravated anaphylactic shock when produced by horse serum or egg white, and as measured by per cent mortality, occurrence of lesions in the ileum and hypothermia. Neutralization of the hypoglycemic state by injection of glucose restored the resistance of rats to anaphylactic shock. The degree of hypothermia in anaphylactic shock did not parallel the intensity of the lesions or the per cent mortality.
Br. J. Pharmac. Chemother. (1967), 31, 351-355.
THE RELATIONSHIP OF THE BLOOD SUGAR LEVEL TO THE SEVERITY OF ANAPHYLACTIC SHOCK
H. L. DHAR, R. K. SANYAL AND G. B. WEST*
In rats and mice, the severity of anaphylactic shock is altered by changes in the
concentration of glucose in the blood. When hypoglycaemia is induced by Bordetella
pertussis vaccine or insulin, shock is potentiated whereas in hyperglycaemia induced by injections of alloxan or glucose shock is delayed and severity is decreased.
