Browsing articles from "March, 2012"
Res Clin Stud Headache. 1978;6:110-6. Role of individual free fatty acids in migraine. Anthony M. Total plasma free fatty acids, platelet serotonin content and plasma stearic, palmitic, oleic and linoleic acids were estimated in 10 migraine patients before, during and after a migraine attack. Total and individual plasma free fatty acid levels rose and platelet [...]
Also see: PUFA, Fish Oil, and Alzheimers Biochemistry. 1998 Jan 13;37(2):552-7. Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal. Humphries KM, Yoo Y, Szweda LI. During the progression of certain degenerative conditions, including myocardial ischemia-reperfusion injury, mitochondria are a source of increased free-radical generation and exhibit declines in respiratory function(s). It has therefore been suggested that [...]
J Natl Cancer Inst Monogr. 2000;(27):95-112. Tissue-specific synthesis and oxidative metabolism of estrogens. Jefcoate CR, Liehr JG, Santen RJ, Sutter TR, Yager JD, Yue W, Santner SJ, Tekmal R, Demers L, Pauley R, Naftolin F, Mor G, Berstein L. Estrogen exposure represents the major known risk factor for development of breast cancer in women and [...]
J Natl Cancer Inst Monogr. 2000;(27):95-112. Tissue-specific synthesis and oxidative metabolism of estrogens. Jefcoate CR, Liehr JG, Santen RJ, Sutter TR, Yager JD, Yue W, Santner SJ, Tekmal R, Demers L, Pauley R, Naftolin F, Mor G, Berstein L. Estrogen exposure represents the major known risk factor for development of breast cancer in women and [...]
Also see: Fat Tissue and Aging – Increased Estrogen J Gerontol. 1978 Mar;33(2):191-6. Circulating plasma levels of pregnenolone, progesterone, estrogen, luteinizing hormone, and follicle stimulating hormone in young and aged C57BL/6 mice during various stages of pregnancy. Parkening TA, Lau IF, Saksena SK, Chang MC. Young (3-5 mo of age) and senescent (12-15 mo of [...]
“Niacinamide, used in moderate doses, can safely help to restrain the excessive production of free fatty acids, and also helps to limit the wasteful conversion of glucose into fat.” “Niacinamide, one of the B vitamins, provides energy to the mitochondrial system. Under stress and strong excitation, cells waste niacinamide NADH, but niacinamide itself has a [...]
On the level of the whole organism, stress causes overactivity of the pituitary, and removal of the pituitary extends life, and retards the hardening of the extracellular connective material (Everitt, et al., 1983). -Ray Peat, PhD Mech Ageing Dev. 1983 Jul-Aug;22(3-4):233-51. The anti-aging action of hypophysectomy in hypothalamic obese rats: effects on collagen aging, age-associated [...]
Muscle catabolism also releases a large amount of cysteine, and cysteine, methionine, and tryptophan suppress thyroid function (Carvalho, et al., 2000). -Ray Peat, PhD Muscle protein is very rich in tryptophan and cysteine, and these amino acids suppress the thyroid gland’s function, and are potentially toxic to nerves, especially in the presence of cortisol and [...]
British Medical_Journal, 1975, 2, 245-248 Oral Contraceptives and Death from Myocardial Infarction J. I. MANN, W. H. W. INMAN We investigated 219 deaths from myocardial infarction in women under the age of 50. Their histories were compared with those of living age-matched controls selected from the same general practices. The frequency of use of oral [...]
Arteriosclerosis. 1986 Jul-Aug;6(4):418-21. Sex hormone levels in young Indian patients with myocardial infarction. Sewdarsen M, Jialal I, Vythilingum S, Desai R. The finding of abnormal levels of sex hormones in men with coronary artery disease has led to the hypothesis that alterations in sex hormones may represent an important risk factor for myocardial infarction. In [...]