Browsing articles from "November, 2011"
Cells, Gels and the Engines of Life
January 2009 The Journal of Lipid Research, 50, 1-2. Endotoxin in the gut and chylomicrons: translocation or transportation? Carl Grunfeld 2 and Kenneth R. Feingold, Associate Editor The intestine contains trillions of microorganisms and massive amounts of endotoxin, which if absorbed from the intestinal lumen into the body would result in overwhelming septic shock and [...]
The fish oil mega industry as we know it today began as the paint/varnish sector dried up when the petroleum industry took over that market. The fish oil industry had no other place to sell this waste product of fish production so they capitalized on the faulty research done by the Burrs’ in the late [...]
Lactate increases blood viscosity, mimics stress, causes inflammation, and contributes to shock. Lactated Ringer’s solution contributes to the tissue damage caused by shock, when it’s used to resuscitate shock victims (Deree, et al., 2007, 2008): it contributes to the inflammatory processes associated with shock, unlike the use of hypertonic saline and other solutions. Lactate contributes [...]
Cancer Res. 1985 May;45(5):1997-2001. Requirement of essential fatty acid for mammary tumorigenesis in the rat. Ip C, Carter CA, Ip MM. In an attempt to determine the requirement of essential fatty acid for dimethylbenz(a)anthracene-induced mammary tumorigenesis, rats were fed diets containing different levels of linoleate: 0.5, 1.1, 1.7, 2.2, 3.5, 4.4, 8.5, or 11.5%. Each [...]
Gastroenterology. 1995 Aug;109(2):547-54. Dietary saturated fatty acids: a novel treatment for alcoholic liver disease. Nanji AA, Sadrzadeh SM, Yang EK, Fogt F, Meydani M, Dannenberg AJ. BACKGROUND & AIMS: Lipid peroxidation may be important in the pathogenesis of alcoholic liver injury. The purpose of this study was to determine whether a saturated fatty acid-based therapy [...]
J Clin Invest. 1993 Mar;91(3):1028-34. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. Harris HW, Grunfeld C, Feingold KR, Read TE, Kane JP, Jones AL, Eichbaum EB, Bland GF, Rapp JH. The hypertriglyceridemia of infection was traditionally thought to represent the mobilization of substrate to fuel the body’s response [...]
Hepatology. 2010 Oct;52(4):1322-33. Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents. Yu LX, Yan HX, Liu Q, Yang W, Wu HP, Dong W, Tang L, Lin Y, He YQ, Zou SS, Wang C, Zhang HL, Cao GW, Wu MC, Wang HY. Increasing evidence suggests that the presence of endotoxemia is of substantial [...]
Hepatology. 2010 Oct;52(4):1322-33. Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents. Yu LX, Yan HX, Liu Q, Yang W, Wu HP, Dong W, Tang L, Lin Y, He YQ, Zou SS, Wang C, Zhang HL, Cao GW, Wu MC, Wang HY. Increasing evidence suggests that the presence of endotoxemia is of substantial [...]
Hepatology. 2010 Oct;52(4):1322-33. Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents. Yu LX, Yan HX, Liu Q, Yang W, Wu HP, Dong W, Tang L, Lin Y, He YQ, Zou SS, Wang C, Zhang HL, Cao GW, Wu MC, Wang HY. Increasing evidence suggests that the presence of endotoxemia is of substantial [...]